Professor. Department of Pharmacology
Director, NIMH Psychoactive Drug Screening Program
Director, Roth Lab
Roth studies all aspects of GPCR structure and function ranging from the atomic-level analysis of ligand-receptor interactions to in vivo studies. Currently we are focused on members of the serotonin (5-hydroxytryptamine; 5-HT) and opioid receptor families and their accessory proteins. Other goals are to discover and develop novel small molecule probes for in vitro and in vivo validation of molecular targets for therapeutic drug discovery.
BRAIN Initiative Grant – ” Dreadd2.0: An Enhanced Chemogenetic Toolkit”
Address: 4072 Genetic Medicine
UNC-CH School of Medicine
Chapel Hill, NC 27599-7365