Janelia Farm

2015-03-28 10.24.47 pmThe Janelia Research Campus is a research campus of the Howard Hughes Medical Institute focusing on neuroscience and imaging.

Chemists, physicists, computational scientists, and engineers work in close collaboration with biologists to tackle problems in neuroscience and imaging. At the interface of these two research areas are approaches to map the structure of neural circuits and monitor their function during animal behavior.

Gerry Rubin video on Janelia Research uploaded by Loudoun County Va.

Web Information

Website:   janelia.org/
Facebook: acebook.com/HHMIJRC
Wikipedia Entry:  wiki/Janelia_Farm_Research_Campus

Contact Information

Emailjanelia.org/content/feedback
Phone: (571) 209-4000
Address: 19700 Helix Drive | Ashburn, VA 20147

Organization

Executive Director: Gerry Rubin
People

The Campus

At the Janelia Research Campus scientists from many disciplines gather to collaborate closely, in small teams, on some of science’s most challenging problems. The architectural design of the buildings and the laboratories helps achieve Janelia’s central objectives—collaboration and flexibility. Every element, from the sweeping laboratory building—organized around curving glass corridors punctuated by soaring glass-enclosed staircases—to the 96-room guest house and adjacent housing village, is intended to foster collaboration. Janelia website

The Janelia Research Campus is located in Loudoun County, Virginia, near the town of Ashburn.The 689 acres campus  features a 900-foot long, arc-shaped laboratory known as the Landscape Building. Designed by Rafael Viñoly, the building, 270 feet (82 m) deep at the ground floor, is built into a hill and designed to be the primary research facility. Site and landscape design were completed by Dewberry in 2006 and include over four acres of green roof meadow plantings which blend the building into the surrounding site. Additional landscape enhancements were designed by Lewis Scully Gionet, Inc., and were completed in fall 2008 (and won an Honor Award from the Maryland and Potomac chapters of the American Society of Landscape Architects). This work includes hardscape elements (an architectural water feature, expanded path network, and siting of multiple pieces of artwork, among others) and comprehensive planting additions, and was constructed by Ruppert Nurseries. From Wikipedia 2/20/15

Below is a gallery of photos of the campus taken by Janelia’s design firm Rafael Viñoly Architects, PC. Click on images to view.

Research

From Janelia website

The Janelia Research Campus enables scientists from different disciplines to collaborate in creating and exploiting new tools to advance biomedical science.

Janelia researchers pursue long-term projects of high significance—projects that could not fit within the confines of a standard grant proposal. Currently, Janelia scientists are working on some of science’s most challenging problems: discovering the basic rules and mechanisms of the brain’s information-processing system and developing optical, biological, and computational technologies for creating and interpreting biological images.

At Janelia, leading scientists can pursue long-range research projects in a campus specially designed to bring together researchers from disparate disciplines. Biologists work alongside computer scientists, engineers, physicists, and chemists in an environment free of the traditional disciplinary boundaries one might encounter in academia. Research teams are small and team leaders are actively involved in research; they are not just managing it or guiding it. HHMI provides funding for all research at Janelia.

For many years, the main way HHMI conducted research was through supporting investigators who worked at their home institution. This is still the majority of HHMI research, with (as of 2011) more than 330 investigators at 70 institutions. However, there are interdisciplinary problems that are difficult to address in existing research settings, and Janelia was built to address one of these problems,neurobiology. As of November 2011, the facility has 424 employees and room for 150 more. The campus focuses on interdisciplinary research in this area, specifically addressing:

  • The identification of general principles that govern how information is processed by neuronal circuits.
  • The development of imaging technologies and computational methods for image analysis.

In addition to and in cooperation with the individual investigators, there are three large scale interdisciplinary projects at Janelia:

  • High-throughput characterizing of the behavioral phenotypes on genetically defined small neural lesions in Drosophila.
  • Two projects aimed at developing both large-scale neuroanatomical data for Drosophila (at the light and electron microscopy levels) as well as accelerating the technology so that even larger anatomical projects can be approached in the future.

Janelia was designed to emulate the unconstrained and collaborative environments at AT&T Bell Laboratories and Cambridge’s Laboratory of Molecular Biology. Researchers are on six-year contracts and fully internally funded, independent of traditional research grant funding.

From Nature, Journal of Science 11/16/11

More significantly, the campus embodies what Rubin calls “an experiment in scientific culture”1. Put world-class researchers in an environment that makes it easy to interact across disciplines — right down to chance encounters around the coffee urns (see’Cultivating collaboration’). Then put them to work on a handful of grand scientific challenges — long-term, high-risk, high-payoff research that addresses some of the biggest questions in neuroscience. And use the HHMI’s ample chequebook to free them from the distractions of conventional academic life. No administrative work, no teaching duties, no chasing tenure, no writing of grants. “This really is the ivory tower,” says Rubin, who was named director of the campus in 2003 and has been involved with the facility since its inception.

But what happens next? Can Janelia Farm do ‘great science’ during the next 5 to 10 years? Will it pass Rubin’s deletion test? Can it rewrite the introductory biology texts (Cech’s favourite definition of great science), or foster “a couple of programmes that create a whole new direction” (Tjian’s favourite)?

That is the great unanswerable question. As Simpson says, “you can’t engineer great science. You just have to create the conditions that make it possible, and see what happens.”

Research Labs

From Janelia website

  • AHRENS LAB

    Systems & Behavioral Neuroscience / Theoretical & Computational Neuroscience

  • BAKER LAB

    Cellular, Developmental & Behavioral Neuroscience / Genetics / Molecular Biology

  • BETZIG LAB

    Optical Physics / Engineering / Instrument Design

  • BOCK LAB

    Neuroanatomy / Systems & Behavioral Neuroscience / Instrument Design

  • BRANSON LAB

    Computer Science / Mathmatics / Systems & Behavioral Neuroscience

  • CARD LAB

    Systems & Behavioral Neuroscience / Electrophysiology / Instrument Design

  • CARDONA LAB

    Systems & Behavioral Neuroscience

  • CUI LAB

    Optical Physics / Engineering / Instrument Design

  • DICKSON LAB

  • DRUCKMANN LAB

    Theoretical & Computational Neuroscience/Systems Neuroscience

  • DUDMAN LAB

    Systems & Behavioral Neuroscience/ Computational Neuroscience / Electrophysiology

  • EDDY/RIVAS LAB

    Computational Genomics

  • FREEMAN LAB

  • GONEN LAB

    Structural Biology / Biochemistry / Electrophysiology / Biophysics

  • GRIGORIEFF LAB

    Computer Science / Mathematics, Structural BIology / Biochemistry

  • HANTMAN LAB

    Systems & Behavioral Neuroscience / Cellular & Developmental Neuroscience

  • HARRIS LAB – APIG

    Engineering / Instrument Design / Optical Physics / Nanofabrication

  • HEBERLEIN LAB

    Behavioral Neuroscience / Genetics / Molecular Biology

  • HESS LAB

    Optical Physics / Engineering / Instrument Design

  • JAYARAMAN LAB

    Systems & Behavioral Neuroscience / Computational Neuroscience / Instrument Design

  • JI LAB

    Optical Physics / Instrument Design / Cellular & Systems Neuroscience

  • KARPOVA LAB

    Systems & Behavioral Neuroscience / Computational Neuroscience / Molecular Tool Development

  • KELEMAN LAB

  • KELLER LAB

    Developmental Neurobiology / Bioimage Informatics / Optical Physics / Microscope Design

  • KOYAMA LAB

    Cellular & Developmental Neuroscience / Electrophysiology / Systems & Behavioral Neuroscience / Neuroanatomy

  • LAVIS LAB

    Synthetic Chemistry / Biochemistry / Molecular Tool Development

  • LEE (ALBERT) LAB

    Systems & Behavioral Neuroscience / Electrophysiology / Instrument Design

  • LEE (TZUMIN) LAB

    Cellular & Developmental Neuroscience / Neuroanatomy / Genetics / Molecular Biology

  • LEONARDO LAB

    Systems & Behavioral Neuroscience / Theoretical & Computational Neuroscience / Instrument Design

  • LIU LAB

  • LOOGER LAB

    Protein Engineering / Molecular Tool Development / Structural Biology / Biochemistry

  • MAGEE LAB

    Cellular Neuroscience / Systems & Behavioral Neuroscience/ Electrophysiology

  • MURPHY LAB

    Systems & Behavioral Neuroscience / Electrophysiology / Neuroanatomy

  • PASTALKOVA LAB

    Systems & Behavioral Neuroscience / Theoretical & Computational Neuroscience

  • REISER LAB

    Systems & Behavioral Neuroscience / Computational Neuroscience / Instrument Design

  • RIDDIFORD LAB

    Cellular, Developmental & Behavioral Neuroscience / Developmental Endocrinology

  • ROMANI LAB

    Theoretical & Computational Neuroscience

  • RUBIN LAB

    Molecular Tool Development / Neuroanatomy / Genetics / Behavioral Neuroscience

  • SAALFELD LAB

    Image Processing, Image Analysis, Pattern Recognition, Computer Vision, Machine Perception, Computer Science, Software Engineering

  • SIMPSON LAB

    Systems & Behavioral Neuroscience / Neuroanatomy / Genetics / Molecular Biology

  • SINGER LAB

    Genetics / Molecular Biology / Structural Biology / Biochemistry

  • SPRUSTON LAB

    Cellular & Systems Neuroscience / Electrophysiology / Neuroanatomy / Computational Neuroscience

  • STERN LAB

    Evolutionary Biology / Developmental Biology / Molecular Biology / Behavioral Neuroscience / Genetics

  • STERNSON LAB

    Systems & Behavioral Neuroscience / Synthetic Chemistry / Protein Engineering / Molecular Tool Development

  • SVOBODA LAB

    Systems & Behavioral Neuroscience / Cellular & Developmental Neuroscience / Neuroanatomy / Instrument Design

  • TJIAN LAB

    Biochemistry / Molecular Biology / Optical Physics / Instrument Design / Structural Biology

  • TRUMAN LAB

    Cellular, Developmental & Behavioral Neuroscience / Neuroanatomy / Evolutionary Biology

  • TURAGA LAB

  • WU LAB

    Genetics / Molecular Biology / Structural Biology/Biochemistry

  • ZLATIC LAB

    Cellular, Developmental & Behavioral Neuroscience / Neuroanatomy

  • ZUKER LAB

    Systems & Behavioral Neuroscience / Cellular Neuroscience

 

Some videos from Labs below

Here’s a playlist of popular Janelia videos that includes the two videos below.

 

 

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