Patrick Kanold

Associate Professor of Biology
Director, Kanold Lab

Dr. Kanold studies the development and plasticity of the brain, in particular how periods of learning and plasticity are initiated and controlled. His work focuses on the development of the central auditory and visual system in particular on the role of early cortical circuits in brain wiring. He uses advanced neurophysiological, in vivo imaging, optogenetic, molecular and computational techniques.

John Maunsell

Professor, Department of Neurobiology
Director, Grossman Institute for Neuroscience, Quantitative Biology and Human Behavior

Maunsell’s research is aimed at understanding how neuronal signals in visual cerebral cortex generate perceptions and guide behavior. Our approach is to record from individual neurons in trained, behaving monkeys and mice while they perform visual tasks. Another line of research has been exploring the more general question of how the activity of given neurons contributes to specific visual behaviors.

David Kleinfeld

Professor of Biophysics
Director, David Kleinfeld Laboratory

David Kleinfeld and his colleagues take biophysical and computational approaches to bridge phenomena at different levels in the brain, ranging from intracellular electrophysiology to multi-cellular recording to animal behavior. This provides an opportunity to discover algorithms and principles that underlie computations within nervous systems. In additional, they develop instrumentation and analysis procedures that facilitate the study of physiology.

Fritjof Helmchen

Professor, Departement of Neurophysiology
Director, Laboratory of Neural Circuit Dynamics

Helmchen is characterizing the properties of individual neurons in vivo and investigate how synaptic inputs are integrated in their dendrites to eventually cause action potentials that are transmitted to target neurons. Using in vivo electrophysiology and 2-photon imaging we perform both intracellular recordings from individual neurons as well as optical measurements of population activity. Development of 2-photon microscopy techniques for high-resolution imaging in living and behaving rodents.

Kit S. Lam

Professor and Chair, Department of Biochemistry and Molecular Medicine
Professor, Hematology and Oncology
Director, Kit Lamb Lab

Dr. Lam is an expert in combinatorial chemistry, chemical biology, drug development, molecular imaging, nanotherapeutics and medical oncology. His laboratory is engaged in the development and application of combinatorial library methods for basic research and drug discovery. Lam is also interested in signal transduction, antibiotics development, molecular immunology, chemical microarray, and proteomics.

Lihong Wang

Professor of Biomedical Engineering
Director, Optical Imaging Laboratory

His lab reported the first functional photoacoustic tomography, 3D photoacoustic microscopy (PAM), optical-resolution PAM, photoacoustic Doppler effect, photoacoustic reporter gene imaging, microwave-induced thermoacoustic tomography, the universal photoacoustic reconstruction algorithm, frequency-swept ultrasound-modulated optical tomography, time-reversed ultrasonically encoded (TRUE) optical focusing, sonoluminescence tomography, Mueller-matrix optical coherence tomography, and optical coherence computed tomography.

Euisik Yoon

Professor of Electrical Engineering and Computer Science and Biomedical Engineering
Principal Investigator, Yoon Lab

Yoon’s research group realizes self-contained microsystems that combine and process natural signals (such as bio, chemical, optical and thermal signals) as well as electrical signals on a single chip platform by integrating new MEMS/nano structures with low-power, wireless VLSI circuits and systems.

Julie Brefczynski-Lewis

Research Assistant Professor, Department of Physiology
Director, Brefczynski-Lewis Lab

Brefczynski-Lewis studies how we perceive people we love and people we don’t like, both famous and political, and how training in compassion can affect those perceptions. She is examining the neural and physiological correlates of the liked and disliked persons and how these change after training in compassion. Grudge forgiveness study: fMRI response to the face of the grudge person, as well as cardio and reactive measures will be tested before and after the intervention.

Bryan Roth

Professor in Department of Pharmacology
Director, NIMH Psychoactive Drug Screening Program
Director, Roth Lab

Roth studies all aspects of GPCR structure and function ranging from the atomic-level analysis of ligand-receptor interactions to in vivo studies. Currently we are focused on members of the serotonin (5-hydroxytryptamine; 5-HT) and opioid receptor families and their accessory proteins. Other goals are to discover and develop novel small molecule probes for in vitro and in vivo validation of molecular targets for therapeutic drug discovery.

John L. R. Rubenstein

Professor of Psychiatry and Child Psychiatry
Director, Rubenstein Lab

Rubenstein’s research focuses on the regulatory genes that orchestrate development of the forebrain. His lab has demonstrated the role of specific genes in regulating neuronal specification, differentiation, migration and axon growth during embryonic development and on through adult life. His work may help to explain some of the mechanisms underlying human neurodevelopmental disorders such as autism.

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