Nenad Sestan

Professor of Neurobiology, of Genetics and of Psychiatry
Director, Sestan Lab

Research Interests- the evolution and development of neuronal circuits of the human cerebral cortex. Research in the Sestan Lab investigates how neurons acquire distinct identities and form precise connections in the developing cerebral cortex, a part of the brain involved in a variety of higher cognitive, emotional, sensory, and motor functions. The Lab also studies how these developmental processes have changed during evolution and in human disorders.

Arnold Kriegstein

Director, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research
Department of Neurology

Kriegstein’s research in our lab focuses on the way in which neural stem and progenitor cells produce neurons, and ways in which this information can be used for cell based therapies to treat diseases of the nervous system. He has found that radial glial cells, long thought to simply guide nerve cells during migration, are neuronal stem cells in the developing brain.

Massimo Scanziani

Professor, Neurobioloby section
Director, Scanziani Lab

The goal of Scanziani’s research is to understand the circuits controlling the spatial and temporal structure of cortical activity. Towards this goal his lab uses in vivo and in vitro electrophysiological, imaging and anatomical approaches. Model systems are the rodent’s somatosensory cortex and hippocampus. His lab focuses on the role played by elementary cortical circuits resulting from the interaction between excitatory and inhibitory neurons.

Daniel H Geschwind

Professor of Human Genetics and of Neurology and Psychiatry, UCLA School of Medicine
Director, Neurogenetics Program and the Center for Autism Research and Treatment (CART)
Co-director, UCLA Center for Neurobehavioral Genetics
Director, Geschwind Lab

Geschwind lleverages genetics and genomics to understand neurodevelopment and neurodegenerative disease mechanisms developing new treatments for these disorders. Dr. Geschwind also fosters large-scale collaborative patient resources for genetic research and data sharing.

Joseph R. Ecker

Professor Plant Molecular and Cellular Biology Laboratory
Howard Hughes Medical Institute and Gordon and Betty Moore Foundation Investigator
Salk International Council Chair in Genetics
Director, Ecker Lab

Ecker is one of the nation’s leading authorities on the molecular biology and genetics of plants. He is interested in understanding the roles of genetic and ‘epigenetic’ processes in cell growth and development thereby understanding the complexity of gene regulatory processes that underlie development and disease in plants and humans.

Joshua R Sanes

Professor of Molecular and Cellular Biology
Director, Sanes Lab and Center for Brain Science

Key questions that Joshua Sanes is exploring is how are complex neural circuits assembled in young animals and how do they process information in adults? To understand how these circuits form, we mark retinal cell types transgenically, map their connections, seek recognition molecules that mediate their connectivity, use genetic methods to manipulate these molecules, and assess the structural and functional consequences of removing or swapping them.

Pavel Osten

Associate Professor, Cold Spring Harbor Laboratory
Principal Investigator: Osten Lab

To understand what’s going wrong in illnesses like autism and schizophrenia, we need to know more about how neural circuits are connected in the healthy brain. We’ve developed advanced imaging methods to draw the first whole-brain activation map in the mouse. Now we’re applying that technology to study changes in brain activity in mice whose behavior models human autism and schizophrenia.

Sacha Nelson

Professor of Biology, Brandeis University
Director, Nelson Lab

Sacha Nelson’s research focuses on understanding the cell types and circuits that comprise the mammalian neocortex, and how these circuits are altered by normal experience and during disease. His work employs a combination of electrophysiology, anatomy and mouse genetics and genomics to define cortical cell types and to identify alterations in cortical connectivity in epilepsy and autism spectrum disorders.

John J. Ngai

Professor of Neurobiology, Coates Family Professor of Neuroscience, Helen Wills Neuroscience Institute
Director, QB3 Functional Genomics Laboratory

My focus is understanding the molecular and cellular mechanisms underlying the function, development and regeneration of the vertebrate olfactory system. My lab uses a wide range of experimental tools and model systems, including molecular biology, genomics, computational biology and behavior to study these processes using the mouse and zebrafish as model systems.

Hongkui Zeng

Senior Director, Research Science
Allen Institute Research and Development

Zeng explores novel technologies and develop high-throughput paradigms for generating large-scale, public datasets and tools to fuel neuroscience discovery. Zeng has broad scientific experience and a keen interest in using a combined molecular, genetic and physiological approach to unravel mechanisms of brain circuitry and potential approaches for treating brain diseases.

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