Laboratory of Neural Circuit Dynamics

Principal Investigator: Fritjof Helmchen
Zurich Brain Research Institute

To study neural circuit function our research is focused on advancing and applying in vivo high-resolution imaging methods, with a particular emphasis on neocortical microcircuitry. The lab’s specific goals are to reveal principles of single-cell and local network computation and to decipher the neural codes governing information processing as well as circuit plasticity.

Two-photon laser-scanning microscopy has become the method of choice for imaging nerual dynamics on the cellular level in the intact brain. The particular advantage of 2-photon microscopy is its reduced sensitivity to light scattering so that individual cells with their dendrites can be resolved several hundreds of micrometers deep in neural tissue in living animals

Two-photon laser-scanning microscopy has become the method of choice for imaging nerual dynamics on the cellular level in the intact brain. The particular advantage of 2-photon microscopy is its reduced sensitivity to light scattering so that individual cells with their dendrites can be resolved several hundreds of micrometers deep in neural tissue in living animals

Web Information

Webpage:  hifo.uzh.ch/research/helmchen.html 
BRAIN Initiative Grant – “Multi-area two-photon microscopy for revealing long-distance communication between multiple local brain circuits”

Contact Information

Email: helmchen@hifo.uzh.ch
Phone: +41 44 635 3340
Address: Winterthurerstrasse 190
8057 Zurich

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